The use of sodium carboxymethyl cellulose CMC in the pharmaceutical industry

In the pharmaceutical industry, it can be used as an emulsion stabilizer for injections, as a binder and film-forming agent for tablets.

It has been proved by basic and animal experiments that CMC is a safe and reliable anticancer drug carrier.

Using sodium carboxymethyl cellulose CMC as the membrane material, the modified dosage form of the traditional Chinese medicine Yangyin Shengji Powder, the Yangyin Shengji San, can be used for skin abrasion and traumatic wounds.

Animal model studies have shown that the membrane prevents wound infection and is not significantly different from gauze dressings. This membrane is significantly better than gauze dressings in controlling wound tissue fluid exudation and rapid wound healing, and has the effect of reducing postoperative edema and wound irritation.

The best prescription is a film made of polyvinyl alcohol: sodium carboxymethyl cellulose: carbopol in a ratio of 3:6:1. The adhesion and release rate are increased, and the mucosal adhesion of the sustained-release film is increased. The adhesion of the agent, prolonging the residence time of the agent in the oral cavity, and the efficacy of the drug in the agent have been significantly improved.

Because bupivaca is a potent local anesthetic, it can sometimes produce more serious cardiovascular side effects when it is poisoned. Therefore, while bupivacaine is widely used clinically, research on the prevention and treatment of its toxicity has been paid more attention.

Pharmaceutical studies have shown that CIVIC as a sustained-release substance and bupivacaine solution can significantly reduce the side effects of the drug.

In PRK surgery, the use of low-concentration decaine and non-steroidal anti-inflammatory drugs combined with sodium carboxymethyl cellulose CMC can significantly relieve postoperative pain.

Preventing peritoneal adhesions after abdominal surgery and reducing the occurrence of intestinal obstruction is one of the most concerned issues in clinical surgery.

Studies have shown that CMC is significantly better than sodium hyaluronate in reducing the degree of postoperative peritoneal adhesions, and can be used as an effective method to prevent peritoneal adhesions.

Carboxymethyl cellulose sodium CMC is used in the catheter hepatic artery infusion of anticancer drugs for the treatment of liver cancer, which can significantly prolong the residence time of anticancer drugs in the tumor, enhance the anti-tumor power, and improve the therapeutic effect.

In animal medicine, CMC also has a wide range of uses. It has been reported that instilling 1% sodium carboxymethyl cellulose CMC solution into the abdominal cavity of ewes has a significant effect in preventing dystocia and abdominal adhesions after reproductive tract surgery in livestock.