2-Chloro-5-Chloromethylthiazole

2-Chloro-5-Chloromethylthiazole, CAS 105827-91-6

Hosea Chem® is a premier China manufacturer and global exporter of high-quality 2-Chloro-5-Chloromethylthiazole (CAS 105827-91-6). We guarantee stable bulk inventory (9,000 MT/year capacity), direct factory pricing, and worldwide shipment with full TDS, MSDS, and COA documentation.

Product Chemical Properties

Product Name: 2-Chloro-5-Chloromethylthiazole

CAS No.: 105827-91-6

Molecular Formula: C₄H₃Cl₂NS 

Molecular Weight: 168.04 

The preparation method of this product is as follows:

The preparation method involves adding 2-chloropropenyl isothiocyanate and chloroform solvent to a reaction flask, followed by the dropwise addition of thiocyanate chloride. The internal temperature is maintained at 30°C. After the addition is complete, the reaction is continued at room temperature for 2.5 hours, during which time the internal temperature rises to 36°C. After the reaction is complete, the solvent and remaining thiocyanate chloride are removed by distillation. The residue is dissolved in dichloromethane, washed with NaHCO3 solution and water respectively, dried, and the solvent is evaporated (under reduced pressure) to obtain the product.

Melting point 31ºC

Density 1.503 g/cm³

Boiling point 268.6ºC

Flash point 116.3ºC

Appearance and shape: White to pale yellow crystals or colorless liquid

Acidity/Alkalinity: Acidic, Reducing

Product Technical Specification

Appearance: Light yellow liquid or light yellow crystal (below 25℃)

Purity: ≥98.5%

Moisture: ≤ 0.1%

Acidity: ≤ 0.3%

    

Applications of 2-Chloro-5-Chloromethylthiazole

Used in the synthesis of pesticides thiamethoxam and thiamethoxam, and pharmaceuticals ritonavir. Thiamethoxam, as a new generation of neonicotinoid insecticides, has attracted much attention in the pesticide industry and has a promising market prospect; ritonavir, as an inhibitor of human immunodeficiency virus (HIV), is indispensable in the absence of a specific drug.

Packaging

250Kg  / Drum, 20MT/20'FCL

  

Production Capacity

9000 MT per year.

Storage Requirements

2-Chloro-5-Chloromethylthiazole should be stored in a well-ventilated, dry environment. Seal tightly after use.

Pharmaceutical Intermediates

2-Chloro-5-Chloromethylthiazole

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